Neonatal Research Institute

Premature infants Receiving Milking or Delayed cord clamping (PREMOD2)

Premature Infants Receiving Milking or Delayed Cord Clamping: A Randomized Controlled Multicenter Non-Inferiority Trial


Delayed cord clamping has been recommended by every international organization because it has been shown to reduce bleeding in the brain. However, the sickest newborns that require resuscitation do not get delayed cord clamping. Cord milking would allow all babies to receive a placental transfusion, however the evidence for this practice is limited. This will be the largest (N=1500 infants) study of premature infants to provide the much needed evidence that cord milking is "non-inferior" to delayed cord clamping.

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